• SEOUL NATIONAL UNIVERSITY

    SYNTHETIC ORGANIC
    CHEMISTRY LAB

  • SEOUL NATIONAL UNIVERSITY

    SYNTHETIC ORGANIC
    CHEMISTRY LAB

  • SEOUL NATIONAL UNIVERSITY

    SYNTHETIC ORGANIC
    CHEMISTRY LAB

WELCOME TO LEE RESEARCH GROUP

Our mission is to address unmet synthetic needs to solve various problems of biomedical research. To this end, novel strategies to access natural and unnatural small molecules, as well as biopolymers, are being investigated. More specifically, we are developing target-oriented syntheses that can rapidly increase the molecular complexity of the desired therapeutics. At the same time, transition metal-based synthetic methods that should allow for the preparation of analogues of biologically important biopolymers are being explored. Eventually, the accumulated knowledge should serve to solve problems associated with important therapeutic issues, such as opioid addiction and antibiotic resistance.

NOTICE

더보기
    등록된 글이 없습니다.

PUBLICATION

더보기
  • Stereospecific Palladium-Catalyzed Cross-Coupling of Alkylboron Compounds: A Short Account

    Byeongdo Roh and Hong Geun Lee* 

  • Dual Function of N-Iodosuccinimide for C(sp3)–B Bond Activation

    Ju Hyun Youn, Su Yong Go, Hyunho Chung, Haeyeon Lee, Taek Dong Chung, Paul Ha-Yeon Chung* and Hong Geun Lee*

  • Mechanistic duality of indolyl 1,3-heteroatom transposition

    Yujin Lee, Yun Seung Nam, Soo Young Kim, Jung Eun Ki and Hong Geun Lee*

  • Stereospecific Acylative Suzuki–Miyaura Cross-Coupling: General Access to Optically Active α-Aryl Carbonyl Compounds

    Byeongdo Roh, Abdikani Omar Farah, Beomsu Kim, Taisiia Feoktistova, Finn Moeller, Kyeong Do Kim, Paul Ha-Yeon Cheong*, and Hong Geun Lee*​

  • A unified synthetic strategy to introduce heteroatoms via electrochemical functionalization of alkyl organoboron reagents

    Su Yong Go‡​, Hyunho Chung‡​, Samuel Jaeho Shin, Sohee An, Ju Hyun Youn, Tae Yeong Im, Ji Yong Kim, Taek Dong Chung*, and Hong Geun Lee*​

  • A tandem process for the synthesis of β-aminoboronic acids from aziridines with haloamine intermediates

    Subin Park‡, Jangwoo Koo‡​, Weonjeong Kim, and Hong Geun Lee*

  • Formation of the Tertiary Sulfonamide C(sp3)–N Bond Using Alkyl Boronic Ester via Intramolecular and Intermolecular Copper-Catalyzed Oxidative Cross-Coupling

    Dong Sun Kim, and Hong Geun Lee*

  • Benzylic C(sp3)–C(sp2) cross-coupling of indoles enabled by oxidative radical generation and nickel catalysis

    Weonjeong Kim‡, Jangwoo Koo‡, and Hong Geun Lee*​

  • Restoration of catalytic activity by the preservation of ligand structure: Cu-catalysed asymmetric conjugate addition with 1,1-diborylmethane

    Changhee Kim‡, Byeongdo Roh‡, and Hong Geun Lee*​

  • Modular Counter-Fischer–Indole Synthesis through Radical-Enolate Coupling

    Hyunho Chung, Jeongyun Kim, Gisela A. González-Montiel, Paul Ha-Yeon Cheong*, and Hong Geun Lee*​

  • BDR_rev.PNG
  • 스크린샷 2024-01-05 143244.png
  • YJL.PNG
  • BDR.PNG
  • SYG.PNG
  • SBP.PNG
  • DSK.PNG
  • JK.PNG
  • CHK.PNG
  • HC.PNG